Bibliographic record
Abstract
OBJECTIVES: We examined whether the early initiation of sexual activity is associated with hypertension in US adults, and whether the timing of first menstruation is meaningful in regard of this association. We also assessed the effect modification by ethnicity. METHODS: Using data from 2001 to 2016 National Health and Nutrition Examination Survey, we included 39 788 women. The association of age at the first sexual intercourse (FSI) and hypertension (SBP ≥ 130 mmHg or DBP ≥ 80 mmHg) was examined using multivariate logistic regression. Effect modification by ethnicity was assessed through a cross-product interaction term between age at FSI and ethnicity. RESULTS: Among women with FSI after their first menstruation, the odds of hypertension decrease by 20% [95% confidence interval (CI) -27 to -13%] in those who experienced FSI after 19 years of age, relative to those with FSI before 19 years of age. Ethnicity significantly modified the inverse association between age at FSI and hypertension (P value for interaction: 0.0003). Among non-Hispanic white, having FSI aged at least 19 years reduced the odds of hypertension by 34% (95% CI -41 to -27%). Turning to Latina women, the FSI before 19 years of age and before first menstruation resulted to a marked increase in the odds of hypertension [odds ratio = 1.38 (95% CI 1.15-1.65)]. In non-Hispanic black, the age at FSI was not linked to hypertension. CONCLUSION: The FSI before 19 years of age is associated with hypertension during adulthood in US non-Hispanic white and Hispanic women, but not in non-Hispanic black.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".