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Record W2810458359 · doi:10.1016/j.jpeds.2018.06.008

T-Cell Receptor Excision Circles in HIV-Exposed, Uninfected Newborns Measured During a National Newborn Screening Program for Severe Combined Immunodeficiency

2018· article· en· W2810458359 on OpenAlexaff
Josiane Warszawski, Caroline Thomas, Olivia Dialla, Valérie Garrait, Catherine Dollfus, Véronique Reliquet, Laure Clech, Cécile Dert, Laurent Mandelbrot, Marie Audrain, Stéphane Blanche, Catherine Crenn‐Hébert, Corinne Floch-Tudal, Fabienne Mazy, Marine Joras, Françoise Meier, Emmanuel Mortier, Sophie Matheron, Neila Elaoun, Lahcene Allal, Sandrine Djoubou, Djamila Rahli, Agnès Bourgeois Moine, M. Valentin, Claudine Touboul, Lanto Ratsimbazafy, Emilie Boiron, Brigitte Elharrar, Marine Driessen, Pierre Frange, Florence Veber, Roland Tubiana, Marc Dommergues, Luminata Shneider, Fabienne Caby, Ruxandra-Oana Calin, Mohamed Amine Yangui, Didier Roca, Darina Todorova, L. Blum, V. Chambrin, Eric Lachassine, L. Benoist, Vincent Jeantils, Amélie Benbara, Lionel Carbillon, Marie‐Dominique Tabone, Mary‐France Courcoux, Gilles Kayem, Véronique Reliquet, Cécile Brunet-Cartier, Norbert Winer, E. Vaucel, Thierry Wack, Isabelle Leymarie, Lamya Ait Si Selmi, Fazia ait Benali, Maud Brossard

Bibliographic record

VenueThe Journal of Pediatrics · 2018
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsHotel Dieu Hospital
FundersAgence Nationale de Recherches sur le Sida et les Hépatites Virales
KeywordsMedicineHuman immunodeficiency virus (HIV)Severe combined immunodeficiencyNewborn screeningImmunodeficiencyPediatricsVirologyImmunologyGeneticsBiologyImmune system

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.739
Threshold uncertainty score0.754

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.247
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2018
Admission routes1
Has abstractno

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