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Machine learning for integrating data in biology and medicine: Principles, practice, and opportunities

2018· article· en· 642 citations· W2810986024 on OpenAlex· 10.1016/j.inffus.2018.09.012

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
none
Consensus categories
none
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Not applicableConsensus signal: none
Genre
Candidate signal: EmpiricalConsensus signal: Empirical
Teacher disagreement score
0.976
Threshold uncertainty score
0.182
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.065
GPT teacher head0.355
Teacher spread
0.290 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Information Fusion
Topic
Gene expression and cancer classification
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
SickKids FoundationVector InstitutePrincess Margaret Cancer CentreUniversity of Toronto
Funders
National Institute of Biomedical Imaging and BioengineeringNatural Sciences and Engineering Research Council of CanadaNational Science Foundation
Keywords
Data scienceComputer scienceSystems biologyIdentification (biology)EpigenomeSystems medicineField (mathematics)ImplementationData integrationBig dataGrand ChallengesBioinformaticsData miningBiology
Has abstract in OpenAlex
no