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Parametric Analysis of Renal Failure Data using the Exponentiated Odd Weibull Distribution

2018· article· en· W2811213454 on OpenAlexvenueno aff
Kahadawala Cooray, Nonhle Channon Mdziniso

Bibliographic record

VenueInternational Journal of Statistics in Medical Research · 2018
Typearticle
Languageen
FieldMathematics
TopicStatistical Distribution Estimation and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsWeibull distributionCensoring (clinical trials)Parametric statisticsStatisticsHazard ratioSurvival analysisProportional hazards modelParametric modelMathematicsComputer science

Abstract

fetched live from OpenAlex

In this article, we analyze renal failure data from patients with mesangioproliferative glomerulonephritis (MPGN) which was modeled by [1] non-parametrically using the Kaplan-Meier curve. In their work, they showed that the clinical variables, large increase serum creatinine (LISC) and systolic blood pressure >160 mmHg (SBP>160), and morphological variables, benign nephrosclerosis present (BNP) and interstitial score group 5-6 (IS5-6) were part of the variables which indicated progression to end-stage renal failure (ESRF). Though survival curves associated with these variables may be difficult to model by existing parametric distributions in literature. Therefore, we introduce a four-parameter Odd Weibull extension, the exponentiated Odd Weibull (EOW) distribution which is very versatile in modeling lifetime data that its hazard function exhibits ten different hazard shapes as well as various density shapes. Basic properties of the EOW distribution are presented. In the presence of random censoring, a small simulation study is conducted to assess the coverage probabilities of the estimated parameters of the EOW distribution using the maximum likelihood method. Our results show that the EOW distribution is very convenient and reliable to analyze the MPGN data since it provides an excellent fit for the variables LISC, SBP>160, BNP, and IS5-6. Furthermore, advantages of using the EOW distribution over the Kaplan-Meier curve are discussed. Comparisons of the EOW distribution with other Weibull-related distributions are also presented.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.049
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.929
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.049
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0020.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.324
GPT teacher head0.566
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2018
Admission routes1
Has abstractyes

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