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Record W2847899381 · doi:10.1016/j.trci.2018.06.004

The My Active and Healthy Aging (My‐AHA) ICT platform to detect and prevent frailty in older adults: Randomized control trial design and protocol

2018· article· en· W2847899381 on OpenAlexaff
Mathew J. Summers, Innocenzo Rainero, Alessandro Vercelli, Georg Aumayr, Helios De Rosario, Michaela Mönter, Ryuta Kawashima, M. Caglio, Chiara Carbone, Elisa Rubino, Inês Sousa, Maria João M. Vasconcelos, Pedro Madureira, João Carlos Ribeiro, Nuno Cardoso, Eleftheria Giannouli, Wiebren Zijlstra, Sandra Alonso, Sebastian Schnieder, S.D. Roelen, L. Kächele, Jarek Krajewski, J. Laparra, Jaume Serrano, Enrique Medina, J.F. Pedrero, Úrsula Faura Martínez, Marco Bazzani, C. Cogerino, Gregory Toso, G. Tommasone, A. Frisello, Georges M. Haider, D. Bleier, Noemi Sturm, Nico Kaartinen, Andrew Kern, Stephan Bandelow, Nils Georg Niederstrasser, Daryoush Daniel Vaziri, Andrew Tabatabaei, Philip Gouverneur, P. Lagodzinski, Rainer Wieching, M. Grzegorek, H. Shariat Yazdi, Kunji Shirahama, Volker Wulf, Young Seok Cho, Dalila Burin, Rui Nouchi, Ludovico Ciferri

Bibliographic record

VenueAlzheimer s & Dementia Translational Research & Clinical Interventions · 2018
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsInstitute of Aging
FundersNational Health and Medical Research CouncilMedical Research CouncilEuropean CommissionEli Lilly and Company
KeywordsMedicinePsychosocialRandomized controlled trialPsychological interventionGerontologyPopulationPopulation ageingPhysical therapyPsychiatryEnvironmental health

Abstract

fetched live from OpenAlex

INTRODUCTION: Frailty increases the risk of poor health outcomes, disability, hospitalization, and death in older adults and affects 7%-12% of the aging population. Secondary impacts of frailty on psychological health and socialization are significant negative contributors to poor outcomes for frail older adults. METHOD: The My Active and Healthy Aging (My-AHA) consortium has developed an information and communications technology-based platform to support active and healthy aging through early detection of prefrailty and provision of individually tailored interventions, targeting multidomain risks for frailty across physical activity, cognitive activity, diet and nutrition, sleep, and psychosocial activities. Six hundred adults aged 60 years and older will be recruited to participate in a multinational, multisite 18-month randomized controlled trial to test the efficacy of the My-AHA platform to detect prefrailty and the efficacy of individually tailored interventions to prevent development of clinical frailty in this cohort. A total of 10 centers from Italy, Germany, Austria, Spain, United Kingdom, Belgium, Sweden, Japan, South Korea, and Australia will participate in the randomized controlled trial. RESULTS: Pilot testing (Alpha Wave) of the My-AHA platform and all ancillary systems has been completed with a small group of older adults in Europe with the full randomized controlled trial scheduled to commence in 2018. DISCUSSION: The My-AHA study will expand the understanding of antecedent risk factors for clinical frailty so as to deliver targeted interventions to adults with prefrailty. Through the use of an information and communications technology platform that can connect with multiple devices within the older adult's own home, the My-AHA platform is designed to measure an individual's risk factors for frailty across multiple domains and then deliver personalized domain-specific interventions to the individual. The My-AHA platform is technology-agnostic, enabling the integration of new devices and sensor platforms as they emerge.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.659
Threshold uncertainty score0.755

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.246
GPT teacher head0.523
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2018
Admission routes1
Has abstractyes

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