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Record W2855009822 · doi:10.1371/journal.pmed.1002591

Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

2018· review· en· W2855009822 on OpenAlexaff
Elizabeth Harausz, Anthony J. Garcia‐Prats, Stephanie Law, H. Simon Schaaf, Tamara Kredo, James A. Seddon, Dick Menzies, Anna Turkova, Jay Achar, Farhana Amanullah, Pennan M. Barry, Mercedes C. Becerra, Edward D. Chan, Pei‐Chun Chan, Domnica Chiotan, Aldo Crossa, Peter Drobac, Lee Fairlie, Dennis Falzon, Jennifer Flood, Medea Gegia, Robert M. Hicks, Petros Isaakidis, SM Kadri, Beate Kampmann, Shabir A. Madhi, Elsé Marais, Andrei Mariandyshev, Ana Méndez‐Echevarría, Brittany K. Moore, Parpieva Nargiza, Iveta Ozere, Nesri Padayatchi, Saleem- ur-Rehman, Natasha Rybak, Neha Shah, Sangeeta Sharma, Tae Sun Shim, Alena Skrahina, Antoni Soriano‐Arandes, Martin van den Boom, Marieke J. van der Werf, Tjip S. van der Werf, Bhanu Williams, Elena Yablokova, Jae‐Joon Yim, Jennifer Furin, Anneke C. Hesseling

Bibliographic record

VenuePLoS Medicine · 2018
Typereview
Languageen
FieldMedicine
TopicTuberculosis Research and Epidemiology
Canadian institutionsMcGill University
FundersMedical Research CouncilCenters for Disease Control and PreventionFondazione Salvatore MaugeriOtsuka PharmaceuticalUniversity of Cape TownOtsuka Pharmaceutical Development and CommercializationIndus HospitalNew York City Department of Health and Mental HygieneWorld Health OrganizationNational Institute for Health and Care ResearchUnited States Agency for International Development
KeywordsTuberculosisMeta-analysisMedicineSystematic reviewExtensively drug-resistant tuberculosisMEDLINEMultiple drug resistanceIntensive care medicinePediatricsMycobacterium tuberculosisInternal medicineDrug resistancePathologyBiologyGenetics

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Meta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.342
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0200.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.214
GPT teacher head0.410
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations150
Published2018
Admission routes1
Has abstractyes

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