Primary Squamous Cell Carcinoma of the Breast is a Rare and Special Entity
Bibliographic record
Abstract
Background: Primary squamous cell carcinoma of the breast (PSCCB) is a very rare malignancy of the breast. Pure squamous cell carcinoma of the breast can originate from skin adnexa, the nipple or the epithelium of deep-seated epidermoid cyst or squamous metaplasia on chronic inflammation background. Case Report: Our case is a 49-year-old female patient who presented with a highly suspicious lump in her left breast. Bilateral mammography and core biopsy were carried out. The core biopsy was revealed atypical cells and review inconclusive. Incisional biopsy was done and revealed squamous cell carcinoma of the breast (SCCB). Her metastatic work up at presentation was unremarkable. Left-side modified radical mastectomy was carried out. TNM staging was Stage IIa pT2N0M0 GIII, Estrogen receptors (ER) and Progesterone receptors were negative and HER2/Neu was negative as well (Triple negative). Pt had adjuvant chemotherapy and radiotherapy. Eight months later, she developed multiple brain metastasis as solitary site of metastasis, then after four months she developed hepatic and pulmonary deposits. Pt survived only 25 months since disease diagnosis. We report this case with relatively younger age to confirm that primary squamous cell carcinoma of the breast has special aggressive entity and this conjugant with few series. The treatment of primary SqCC of the breast does not differ from other common histological types of breast cancer so far. Conclusions: The prognosis of this disease is highly uncertain and the treatment options are unclear and controversial. There is inadequate literature and treatment guidelines. To our knowledge it is the first case to be reported from arab region with aggressive behavior and short survival period.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".