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<b> <i>Retracted:</i> </b> Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Neuronal Cell Necrosis after Traumatic Brain Injury in Newborn and Juvenile Pigs

2018· article· en· 20 citations· W2883680318 on OpenAlex· 10.1089/neu.2018.5824

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Post-publication record

Nature
Retraction
Reason
Author Unresponsive;Concerns/Issues about Data;Concerns/Issues about Results and/or Conclusions;
Date
4/29/2022 0:00
Flagged by OpenAlex?
Yes

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.

Abstract

Dr. William Armstead, the corresponding author of the article entitled, “Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Neuronal Cell Necrosis after Traumatic Brain Injury in Newborn and Juvenile Pigs” (by Hugh Hekierski, Philip Pastor, Victor Curvello, and William M. Armstead; J Neurotrauma 2019;36(4):630–638; DOI: 10.1089/neu.2018.5824) has requested, via email, a full retraction of the published paper since “substantive questions have arisen regarding the findings, presentation and conclusions reported in the paper that could not be answered with available source data.” On three separate occasions, both the publisher and editor requested additional information detailing the specifics of the questions which were raised that invalidated the findings in the study, but did not receive a response from Dr. Armstead. Despite being unable to ascertain more unambiguous information, the Editor-in-Chief of the Journal of Neurotrauma agreed to Dr. Armstead's request for a retraction after receiving agreements from the article's coauthors. Notably, Dr. Armstead also requested the retraction of two additional articles published in Journal of Neurotrauma,1,2 making the same claim for all three articles. The two other articles are retracted separately.3,4 The editor and publisher of Journal of Neurotrauma is committed to preserving the accuracy of scientific literature. References 1. Armstead, W.M., Riley, J., and Vavilala, M.S. (2017). Sex and age differences in epinephrine mechanisms and outcomes after brain injury. J. Neurotrauma 34, 1666–1675. 2. Armstead, W.M., Riley, J., and Vavilala, M.S. (2016). Norepinephrine protects cerebral autoregulation and reduces hippocampal necrosis after traumatic brain injury via blockade of ERK MAPK and IL-6 in juvenile pigs. J. Neurotrauma 33, 1761–1767. 3. Retraction of: Sex and age differences in epinephrine mechanisms and outcomes after brain injury (DOI: 10.1089/neu.2016.4770). J. Neurotrauma 2022;39 [Epub ahead of print; DOI: 10.1089/neu.2016.4770.retract]. 4. Retraction of: Norepinephrine protects cerebral autoregulation and reduces hippocampal necrosis after traumatic brain injury via blockade of ERK MAPK and IL-6 in juvenile pigs (DOI: 10.1089/neu.2015.4290). J. Neurotrauma 2022;39 [Epub ahead of print; DOI: 10.1089/neu.2015.4290.retract].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Journal of Neurotrauma
Topic
Traumatic Brain Injury and Neurovascular Disturbances
Field
Medicine
Canadian institutions
Funders
Mallinckrodt Pharmaceuticals
Keywords
Traumatic brain injuryMedicineAnesthesiaCerebral autoregulationCerebral blood flowCerebral perfusion pressureAutoregulationHippocampal formationMean arterial pressureBlood pressureInternal medicineHeart rate
Has abstract in OpenAlex
yes