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Record W2884203623 · doi:10.1016/s1473-3099(18)30469-9

Incarceration history and risk of HIV and hepatitis C virus acquisition among people who inject drugs: a systematic review and meta-analysis

2018· review· en· W2884203623 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueThe Lancet Infectious Diseases · 2018
Typereview
Languageen
FieldMedicine
TopicHIV, Drug Use, Sexual Risk
Canadian institutionsQ & T ResearchUniversité de SherbrookeInstitut National de Santé Publique du QuébecAIDS VancouverUniversité LavalUniversité de MontréalUniversity of British ColumbiaCentre Hospitalier de l’Université de Montréal
FundersNational Institute of Allergy and Infectious DiseasesNational Health and Medical Research CouncilFonds de Recherche du Québec - SantéCanadian Institutes of Health ResearchMerck Sharp and DohmeHealth Resources and Services AdministrationNational Institute on Drug AbuseEngineering and Physical Sciences Research CouncilSubstance Abuse and Mental Health Services AdministrationNational Institutes of HealthNorthwestern Polytechnical UniversityDepartment of Health and Aged Care, Australian GovernmentAustralian Agency for International DevelopmentNational Institute for Health and Care ResearchCenter for AIDS Research, University of California, San DiegoMinistère de la Santé et des Services sociauxUniversity of BristolGilead SciencesUniverzita Karlova v PrazeAbbViePublic Health Agency of CanadaADC Foundation
KeywordsMedicineMeta-analysisHepatitis CIncidence (geometry)Cohort studyPsycINFODemographyRelative riskMEDLINEInternal medicineConfidence interval

Abstract

fetched live from OpenAlex

BACKGROUND: People who inject drugs (PWID) experience a high prevalence of incarceration and might be at high risk of HIV and hepatitis C virus (HCV) infection during or after incarceration. We aimed to assess whether incarceration history elevates HIV or HCV acquisition risk among PWID. METHODS: statistic and the P-value for heterogeneity. FINDINGS: =57·3%; p=0·002). Past incarceration was associated with a 25% increase in HIV (RR 1·25, 95% CI 0·94-1·65) and a 21% increase in HCV (1·21, 1·02-1·43) acquisition risk. INTERPRETATION: Incarceration is associated with substantial short-term increases in HIV and HCV acquisition risk among PWID and could be a significant driver of HCV and HIV transmission among PWID. These findings support the need for developing novel interventions to minimise the risk of HCV and HIV acquisition, including addressing structural risks associated with drug laws and excessive incarceration of PWID. FUNDING: Engineering and Physical Sciences Research Council, National Institute for Health Research, National Institutes of Health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.891
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0080.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.335
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it