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Record W2884207681 · doi:10.1017/s146039691800016x

Quality assurance of volumetric-modulated arc therapy head and neck cancer treatment using PRESAGE<sup>®</sup> dosimeter

2018· article· en· W2884207681 on OpenAlexaff
Jalil Ur Rehman, Muhammad Isa, Nisar Ahmad, H. M. Noor ul Huda Khan Asghar, Zaheer Abbas Gilani, James C. L. Chow, Muhammad Afzal, Geoffrey S. Ibbott

Bibliographic record

VenueJournal of Radiotherapy in Practice · 2018
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsPrincess Margaret Cancer Centre
FundersHigher Education Commision, PakistanUniversity of Texas MD Anderson Cancer CenterHigher Education Commission, Pakistan
KeywordsPinnacleNuclear medicineRadiation treatment planningQuality assuranceImaging phantomRadiation therapyThermoluminescent dosimeterDosimeterMedicineDosimetryHead and neckRadiologySurgery

Abstract

fetched live from OpenAlex

Abstract Background Accurate three-dimensional dosimetry is essential in modern radiotherapy techniques such as volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT). In this research work, the PRESAGE ® dosimeter was used as quality assurance (QA) tool for VMAT planning for head and neck (H&amp;N) cancer. Material and method Computer tomography (CT) scans of an Image Radiation Oncology Core (IROC) H&amp;N anthropomorphic phantom with both IROC standard insert and PRESAGE ® insert were acquired separately. Both CT scans were imported into the Pinnacle (9.4 version) TPS for treatment planning, where the structures [planning target volume (PTV), organs at risk) and thermoluminescent detectors (TLDs) were manually contoured and used to optimise a VMAT plan. Treatment planning was done using VMAT (dual arc: 182°–178°, 178°–182°). Beam profile comparisons and gamma analysis were used to quantify agreement with film, PRESAGE ® measurement and treatment planning system (TPS) calculated dose distribution. Results The average ratio of TLD measured to calculated doses at the four PTV locations in the H&amp;N phantom were between 0·95 to 0·99 for all three VMAT deliveries. Dose profiles were taken along the left–right, the anterior–posterior and superior–inferior axes, and good agreement was found between the PRESAGE ® and Pinnacle profile. The mean value of gamma results for three VMAT deliveries in axial and sagittal planes were found to be 94·24 and 93·16% when compared with film and Pinnacle, respectively. The average values comparing the PRESAGE ® results and dose values calculated on Pinnacle were observed to be 95·29 and 94·38% in the said planes, respectively, using a 5%/3 mm gamma criteria. Conclusion The PRESAGE ® dose measurements and calculated dose of pinnacle show reasonable agreement in both axial and sagittal planes for complex dual arc VMAT treatment plans. In general, the PRESAGE ® dosimeter is found to be a feasible QA tool of VMAT plan for H&amp;N cancer treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.454
Threshold uncertainty score0.954

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.388
Teacher spread0.355 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2018
Admission routes1
Has abstractyes

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