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Record W2885401443 · doi:10.3390/polym10080834

How Green is Your Plasticizer?

2018· review· en· W2885401443 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenuePolymers · 2018
Typereview
Languageen
FieldEnvironmental Science
TopicEffects and risks of endocrine disrupting chemicals
Canadian institutionsMcGill University
FundersNatural Sciences and Engineering Research Council of CanadaMitacsMcGill University
KeywordsPlasticizerBiodegradationPolymerLeaching (pedology)Biochemical engineeringMaterials scienceEnvironmental scienceChemistryOrganic chemistryComposite materialEngineering

Abstract

fetched live from OpenAlex

Plasticizers are additives that are used to impart flexibility to polymer blends and improve their processability. Plasticizers are typically not covalently bound to the polymers, allowing them to leach out over time, which results in human exposure and environmental contamination. Phthalates, in particular, have been the subject of increasing concern due to their established ubiquity in the environment and their suspected negative health effects, including endocrine disrupting and anti-androgenic effects. As there is mounting pressure to find safe replacement compounds, this review addresses the design and experimental elements that should be considered in order for a new or existing plasticizer to be considered green. Specifically, a multi-disciplinary and holistic approach should be taken which includes toxicity testing (both in vitro and in vivo), biodegradation testing (with attention to metabolites), as well as leaching studies. Special consideration should also be given to the design stages of producing a new molecule and the synthetic and scale-up processes should also be optimized. Only by taking a multi-faceted approach can a plasticizer be considered truly green.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.979
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.375
Teacher spread0.337 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it