Geohelmintiasis e hiper-IgE en escolares de un área rural y un área urbana de Honduras entre septiembre 2014 a junio 2015
Bibliographic record
Abstract
Introduction: Helminths transmitted by the soil (geohelminths) are the intestinal parasites that provoke the polarization of the immune system towards a response characterized by the high circulating values of Immunoglobulin E (IgE). In Honduras, there are no recent studies demonstrating this biological phenomenon.Objectives: This study aims to determine the association between geohelminth infections with hyper- IgE, comparing schoolchildren from a rural area and an urban area of Honduras.Methodology: Descriptive transversal study. Two communities were selected, with a high prevalence of geohelminths (> 50%) and an urban with low prevalence of geohelminths (<20%). Interviews were conducted with the participants to determine their age, grade and history of deworming. To determine the prevalence of parasites, faecal samples were collected and processed with the Kato-Katz Method and Ethyl Acetate. To determine serum IgE levels, blood samples were taken, and the serum was processed using MagPIX® technology (human Bio-Plex Pro_IgE kit). According to this method the limit of detection for IgE is 0.040 ng / ml. Ethical approval CEI/MEIZ. Parametric and non-parametric statistical analysis.Results: 73 children from the rural area and 71 from the urban area were studied, of which 35 (47.9%) and 5 (7%) were parasitized with one or more species of geohelminths (Trichuris trichiura, Ascaris lumbricoides, hookworm) respectively. Eight participants (<6%) had moderate to severe infections. The rural population presented 94.5% (69) of hyper-IgE in contrast to the urban population with 63.5% (45), (p <0.001). Limitations: there is no history of allergic processes related to IgE.Conclusions: This study was able to determine that there is a significant difference in the IgE levels of children with geohelminth parasites between rural and urban populations. This may explain the decline in allergic reactions in older populations.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.016 | 0.009 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".