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Record W2888684584 · doi:10.1177/1535676018793151

Evaluation of Nine Positive Pressure Suits for Use in the Biosafety Level-4 Laboratory

2018· article· en· W2888684584 on OpenAlex
Samantha Kasloff, Peter Marszal, Hana M. Weingartl

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueApplied Biosafety · 2018
Typearticle
Languageen
FieldEngineering
TopicBiomedical and Engineering Education
Canadian institutionsUniversity of ManitobaCanadian Science Centre for Human and Animal HealthCanadian Food Inspection Agency
Fundersnot available
KeywordsBiosafetyEngineeringWaste managementEnvironmental scienceForensic engineeringToxicologyBiotechnologyBiology

Abstract

fetched live from OpenAlex

Positive pressure suits are the most recognizable feature of Biosafety Level 4 (BSL-4) laboratories, protecting users both through delivery of umbilical-fed HEPA-filtered air and by providing a positively pressurized microenvironment with respect to the surrounding laboratory space to minimize the possibility of exposure resulting from compromised suit integrity. While many positive pressure suits utilized in the chemical and radiation protection industries could be considered for BSL-4 use, the substantial costs and potential incompatibilities with facility settings prevent many labs from investigating novel alternatives. In the present study, 9 positive pressure suits from 5 different manufacturers were critically assessed for their suitability in the BSL-4 laboratory. Material resistance and compatibility with 5% Micro-Chem Plus™, CO2 exposure levels, and overall user preference were assessed through a combination of objective and subjective testing. Results demonstrated that exposure to 5% Micro-Chem Plus™ had no deleterious effects on the mechanical properties of most suit materials, though some potential incompatibility was observed with butyl fabrics. Real-time monitoring of CO2 levels inside the suits showed a great deal of variation between models, however all suits provided a microenvironment where users were exposed to CO2 levels below 1% during normal activity and less than 2% during periods of disconnect from supply air. Finally, survey results from study participants indicated a strong preference for suits with light construction material, 360-degree visibility, high delivery airflow and gloves that require fixation by taping. By combining the present results with facility-specific factors, laboratories will be better equipped to consider new models that best suit their needs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.772
Threshold uncertainty score0.350

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.262
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it