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Record W2888756382 · doi:10.1098/rsbm.2018.0007

Brigitte Alice Askonas. 1 April 1923—9 January 2013

2018· article· en· W2888756382 on OpenAlexaboutno aff
Andrew J. McMichael, Bridget Ogilvie

Bibliographic record

VenueBiographical Memoirs of Fellows of the Royal Society · 2018
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmune Cell Function and Interaction
Canadian institutionsnot available
FundersWellcome Trust
KeywordsRigourIvory towerMedicineReputationLibrary scienceLawPolitical scienceComputer science

Abstract

fetched live from OpenAlex

Brigitte Alice (Ita) Askonas, immunologist and biochemist, was born in Vienna to Czech parents. After an undergraduate degree in Biochemistry at McGill University, Montreal, and a life changing experience as a PhD student in the Department of Biochemistry, University of Cambridge, UK, she spent 36 years at the National Institute for Medical Research (NIMR) where she was a founding member of the Division of Immunology there, eventually becoming its head in 1976 until her formal retirement in 1988. Thereafter, until her death 25 years later, she continued to take an active interest in immunology research, advising scientists at all levels and especially in training young scientists, ensuring they were not mistreated, ignored or not properly acknowledged. Her influence came from her six decades of active involvement in research into many aspects of immunology, studying antibody production, the role of macrophages in antigen recognition and immunosuppression and the role of T lymphocytes in viral infection. This unusually wide experience supported by her biochemical training underlay her reputation for rigour in scientific experimentation, eye for detail and an exacting memory. She was renowned as a scientific mentor and many high-profile scientists learnt their craft in her laboratory and were introduced there into areas of immunology where they subsequently became well known. She was simultaneously very critical and a really good friend who looked after people. She had an exceptionally generous attitude to publication and was thoughtful in many personal ways. She especially valued friends and colleagues who amused her, a quality obvious from her earliest days until the very end of her life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.057
Threshold uncertainty score0.936

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.218
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

Explore more

Same venueBiographical Memoirs of Fellows of the Royal SocietySame topicImmune Cell Function and InteractionFrench-language works237,207