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Record W2889328009 · doi:10.14745/ccdr.v40i03a03

Prolonged Pertussis Outbreak in Ontario Originating in an Under-immunized Religious Community

2014· article· en· W2889328009 on OpenAlexaffvenueabout
SL Deeks, GH Lim, R. Walton, J Fediurek, Freda Lam, Christa Fischer Walker, Jacy Walters, NS Crowcroft

Bibliographic record

VenueCanada Communicable Disease Report · 2014
Typearticle
Languageen
FieldImmunology and Microbiology
TopicBacterial Infections and Vaccines
Canadian institutionsPublic Health OntarioUniversity of TorontoToronto Public Health
Fundersnot available
KeywordsOutbreakPopulationEpidemiologyPublic healthMedicineWhooping coughImmunizationEnvironmental healthTransmission (telecommunications)Community healthDemographyPediatricsVaccinationImmunologyVirologyInternal medicinePathology

Abstract

fetched live from OpenAlex

Abstract. BACKGROUND: A prolonged pertussis outbreak began in Ontario in November 2011 in an under-immunized religious community and subsequently spread to the general population and a second religious community in the same region of the province. OBJECTIVE: To compare the epidemiology in the religious communities to that of the general population within the affected jurisdictions. METHODS: The analysis includes cases reported through the integrated Public Health Information System (iPHIS) between November 1, 2011 and April 15, 2013 that met the outbreak case definition. Health unit staff assessed whether cases were members of religious communities through case investigations and collected information on immunization status, treatment and outcomes. RESULTS: A total of 443 confirmed and probable outbreak cases were reported in 7 health units. The outbreak began in one religious community (138 cases), before spreading to the general population in the region (273 cases). A second under-immunized community within the region experienced 32 cases. Thirteen cases were hospitalized and no deaths were reported. Disease peaked earlier in the religious community; cases were significantly younger, more likely to be at high risk for pertussis and more likely to be unimmunized. Among the fully immunized general population, 51% of cases were between 10-14 years and with a median of 5.6 years since their last immunization. CONCLUSION: The epidemiology of pertussis in the under-immunized community is distinct from the general population. Transmission of pertussis to the general community is not unexpected during an outbreak; however, the proportion of cases up to date with immunization warrants further investigation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.056
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.251
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2014
Admission routes3
Has abstractyes

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