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Record W2890253655 · doi:10.1111/voxs.12446

Moving from a permanent to a 5 year deferral for donors with cured cancer results in a substantial reduction in deferral rates

2018· article· en· W2890253655 on OpenAlexaffabout
Mindy Goldman, Qilong Yi, Sheila F. O’Brien

Bibliographic record

VenueISBT Science Series · 2018
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicEconomic and Financial Impacts of Cancer
Canadian institutionsCanadian Blood Services
Fundersnot available
KeywordsDeferralMedicineDonationSurgeryDemographyCancerBlood donorInternal medicineLawImmunologyFinance

Abstract

fetched live from OpenAlex

Background and Objectives Donor eligibility policies can be precautionary and restrictive, resulting in substantial donation loss. Canadian Blood Services changed from a permanent to a five‐year deferral for most non‐cutaneous cancers following a recently published large‐scale Scandinavian data linkage study. We evaluated the impact of this change on deferral rates. Materials and Methods We assessed the number and rate of deferrals for cancer in the two years before and after the criteria change, and examined computer records of 100 consecutive donors with a history of cancer. Results Overall deferrals declined from 3.1 to 1.1 per 1000 donations. The reduction was similar for males and females, but greater for first time donors (9.4 to 3.2/1000) than repeat donors (2.4 to 0.8/1000). Conclusions Deferrals were substantively reduced, with the greatest impact on new donors. Studies performed in one jurisdiction may benefit donors and ultimately patients in other countries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.231
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.283
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2018
Admission routes2
Has abstractyes

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