Changes in the quality of life of patients with stable ischemic heart disease and preserved left ventricular ejection fraction after coronary artery bypass grafting or stenting at 6-month follow-up
Bibliographic record
Abstract
The aim — to compare the changes of the values of quality of life (QoL) in patients with stable coronary artery disease and preserved left ventricular (LV) ejection fraction (EF) within 6 months after revascularization interventions (coronary artery bypass grafting — CABG, or percutaneous coronary intervention — PCI) and to identify the factors that may affect QoL changes.Materials and methods. A singlecenter prospective study included data from a clinical, instrumental and laboratory examination of 115 patients (91 (79.1 %) men and 24 (20.9 %) women aged 32 to 92 years (mean age — 63 ± 10) with CAD and preserved LV systolic function (LVEF ≥ 45 %) consecutively selected for CABG (n = 71) or coronary stenting (n = 44). QoL was assessed by MLHFQ, SAQ and SF36 questionnaires before and 6 months after myocardial revascularization. Also, changes in the distance of 6minute walking test, Doppler echocardiographic indices of the LV diastolic function and the level of the brain natriuretic peptide (BNP) were analyzed.Results and discussion. After 6 months of followup in the study groups, the levels of QoL according to MLHFQ, SF36 and SAQ scores significantly improved, compared to the baseline data (p < 0.001). In both groups there was a decrease of the functional class of angina by the Canadian classification (p < 0.001). There were no significant differences in the manifestation of stable angina pectoris in the compared groups after 6 months (p = 0.237). Improvement of QoL was associated with decrease of the BNP level from baseline 108.8 (50.1 — 185.4) to 32.3 (12.6 — 57.8) pg/ml in the stenting group (p = 0.002) and from 115.4 (62.0 — 150.6) to 52.4 (20.4 — 95.9) pg/ml in the CABG group (p < 0.001). The distance of the 6minute walk test in the stenting group increased from 223 (148 — 328) m to 550 (400 — 600) m; in the CABG group this distance was, respectively, 260 (195 — 300) and 550 (415 — 600) m.Conclusions. Thus, in patients with stable ischemic coronary disease and preserved LV systolic function after coronary artery stenting or CABG, a significant improvement of QoL values was observed, compared to the baseline data. Favorable changes in QoL may be due to a decrease of angina pectoris, improvement of the Doppler echocardiographic parameters of LV diastolic function and functional status of the patients. The abovementioned changes were associated with decrease of the BNP level.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".