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Recent advancements in the use of exosomes as drug delivery systems

2018· review· en· 583 citations· W2896759930 on OpenAlex· 10.1186/s12951-018-0403-9

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.050
GPT teacher head0.318
Teacher spread
0.268 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Journal of Nanobiotechnology
Topic
Extracellular vesicles in disease
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Fundamental Research Funds for the Central UniversitiesResearch and Innovation FoundationNational Natural Science Foundation of ChinaUniversité Laval
Keywords
MicrovesiclesExosomeExtracellular vesiclesDrug deliveryCellCell biologyExtracellular vesicleCell typeComputational biologyChemistryNanotechnologyBiologymicroRNABiochemistryMaterials science
Has abstract in OpenAlex
yes