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Record W2897276019 · doi:10.1136/vetreccr-2018-000665

Solitary spinal nephroblastoma progressing to multifocal disease in a dog

2018· article· en· W2897276019 on OpenAlexaboutno aff
Sonya Yu, Karon L. Hoffmann, David Taylor, David J. Lurie

Bibliographic record

VenueVeterinary Record Case Reports · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRenal and related cancers
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineParesisLesionSpinal cordSpinal Cord NeoplasmSpinal diseaseHindlimbPathologySurgeryAnatomyLumbar

Abstract

fetched live from OpenAlex

A two‐ year‐old neutered Labrador dog was evaluated for acute onset hindlimb paresis and proprioceptive deficits. Spinal MRI revealed a lesion at the level of T9–T10, from which a presumptive diagnosis of spinal nephroblastoma was made. The dog showed clinical improvement after receiving neoadjuvant stereotactic radiotherapy but re‐presented six weeks later with neurological deterioration. In addition to the primary lesion, a repeat MRI study revealed lesions at T6–T7 and T12. The dog was euthanased and multiple intradural, extramedullary spinal cord lesions were found at postmortem examination. Histopathological analysis of the lesions confirmed spinal nephroblastoma. This report substantiates the likelihood of intraspinal metastases of nephroblastoma occurring in the dog.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0030.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.307
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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