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Record W2901570490 · doi:10.1016/j.envint.2018.11.029

Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013)

2018· article· en· W2901570490 on OpenAlexafffundabout
Amanda Juric, Kavita Singh, Xue Feng Hu, Hing Man Chan

Bibliographic record

VenueEnvironment International · 2018
Typearticle
Languageen
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsUniversity of Ottawa
FundersSocial Sciences and Humanities Research Council of CanadaNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchUniversité du Québec en OutaouaisU.S. Environmental Protection Agency
KeywordsTriclosanEnvironmental healthPopulation healthPopulationEnvironmental scienceMedicine

Abstract

fetched live from OpenAlex

Triclosan is a broad-spectrum antimicrobial additive in consumer products that has been detected in human populations globally. The purpose of this study was to assess triclosan exposure among the Canadian population using urinary triclosan as a biomarker. Data from the Canadian Health Measures Survey (CHMS) that reported triclosan concentrations in 8195 urine samples collected from Cycle 2 (2009-2011) and Cycle 3 (2012-2013) were analyzed. Triclosan was detected in 69.8% of samples with the geometric mean concentrations of 16 μg/L (16 μg/g creatinine) for the total population, 13 μg/L (13 μg/g creatinine) for children (3-19 years of age), and 16 μg/L (17 μg/g creatinine) for adults. Triclosan concentrations significantly differed by age, income, education, and employment in healthcare occupations, but not by race/ethnicity, sex, region of residence, or drinking water preferences or sources. Linear regression models were used to identify factors associated with urinary triclosan concentration. Results showed that household income was associated with higher urinary triclosan concentrations in both children and adults. Employed in healthcare occupations were associated with higher urinary triclosan concentrations in adults. Triclosan exposure at the 99th percentile was below the Biomonitoring Equivalents based on reference dose, suggesting that health risks to the Canadian population from triclosan exposure were low.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.051
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.283
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2018
Admission routes3
Has abstractyes

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