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Record W2903083041 · doi:10.1126/scitranslmed.aau5516

Noncoding regions are the main source of targetable tumor-specific antigens

2018· article· en· W2903083041 on OpenAlexafffund
Céline M. Laumont, Krystel Vincent, Leslie Hesnard, Éric Audemard, Éric Bonneil, Jean‐Philippe Laverdure, Patrick Gendron, Mathieu Courcelles, Marie‐Pierre Hardy, Caroline Côté, Chantal Durette, Charles St-Pierre, Mohamed Benhammadi, Joël Lanoix, Suzanne Vobecky, Élie Haddad, Sébastien Lemieux, Pierre Thibault, Claude Perreault

Bibliographic record

VenueScience Translational Medicine · 2018
Typearticle
Languageen
FieldMedicine
TopicMonoclonal and Polyclonal Antibodies Research
Canadian institutionsCentre Hospitalier Universitaire Sainte-JustineUniversité de MontréalInstitute for Research in Immunology and Cancer
FundersTerry Fox Research InstituteCanadian Cancer SocietyFondation du cancer du sein du Québec
KeywordsAntigenCancer researchComputational biologyBiologyMedicineImmunology

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.344
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations532
Published2018
Admission routes2
Has abstractyes

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