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Record W2903909248 · doi:10.1016/j.jtho.2018.12.005

Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer

2018· article· en· W2903909248 on OpenAlexaff
Yasushi Yatabe, Sanja Đačić, Alain Borczuk, Arne Warth, Prudence A. Russell, Sylvie Lantuéjoul, Mary Beth Beasley, Erik Thunnissen, Giuseppe Pelosi, Natasha Rekhtman, Lukas Bubendorf, Mari Mino–Kenudson, Akihiko Yoshida, Kim R. Geisinger, Masayuki Noguchi, Lucian R. Chirieac, Johan Bolting, Jin-Haeng Chung, Teh‐Ying Chou, Gang Chen, Claudia Poleri, Fernando López‐Ríos, Mauro Papotti, Lynette M. Sholl, Anja C. Roden, William D. Travis, Fred R. Hirsch, Keith M. Kerr, Ming‐Sound Tsao, Andrew G. Nicholson, Ignacio I. Wistuba, André L. Moreira

Bibliographic record

VenueJournal of Thoracic Oncology · 2018
Typearticle
Languageen
FieldMedicine
TopicMedical Imaging and Pathology Studies
Canadian institutionsUniversity of TorontoPrincess Margaret Cancer CentreUniversity Health Network
FundersNational Cancer InstituteNational Institutes of HealthFoghorn TherapeuticsHelsinnAmgenPfizerJapan Society for the Promotion of ScienceGenentechAstraZenecaEli Lilly and CompanyBristol-Myers Squibb
KeywordsMedicineImmunohistochemistryLung cancerCancerOncologyLungPathologyIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gptno category
Domain: not available · Genre: Methods
About the Canadian research system: no · About a Canadian topic: no
Other designmedium
grokno category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
opusno category
Domain: not available · Genre: Other
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.077
metaresearch head score (Gemma)0.212
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.077
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0770.212
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.005
Bibliometrics0.0100.004
Science and technology studies0.0040.004
Scholarly communication0.0090.006
Open science0.0080.006
Research integrity0.0140.019
Insufficient payload (model declined to judge)0.0080.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.548
Teacher spread0.460 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 3 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designOther design · Not applicable
Domainnot available
GenreMethods · Review · Other

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations353
Published2018
Admission routes1
Has abstractno

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