Abbott: Current and next generation ABSORB scaffold
Bibliographic record
Abstract
The ABSORB bioresorbable vascular scaffold (BVSs) has set the stage for the new bioresorbable era as the lead technology of its kind, demonstrating through novel endpoints that the potential advantages of this technology appear to be significant. This chapter details the design and performance features of the ABSORB BVSs. The ABSORB BVSs is coated with everolimus, a semisynthetic antiproliferative macrolide, in poly d,l-lactide in a 1:1 drug:polymer ratio. Development of a bioresorbable vascular scaffold and delivery system to meet the clinical and regulatory needs requires a broad cross-functional product development team. The performance profile of ABSORB BVSs is described by three phases that span its lifecycle: revascularization, restoration, and resorption. The ABSORB BVSs currently has Conformité Européenne (CE) approval and regulatory approval in multiple geographies including the United States, Japan, Korea, Taiwan, India, Brazil, Canada, and Australia and is seeking approval in China.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.094 | 0.049 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".