Current management aspects in adult congenital heart disease: heading for the future
Bibliographic record
Abstract
Current management aspects in adult congenital heart disease: heading for the future There seems to be no area of modern medicine and cardiology that has seen such great successes, as the treatment of congenital heart disease (CHD).While 80 years ago, most children with relevant CHD died in their first years of life, nowadays more than 90% reach adulthood, often with good physical and mental health.This is predominantly the result of advances in cardiac surgery, interventional techniques, intensive care and the use of new drugs.These achievements in the field of adults with congenital heart disease (ACHD) would not have been possible without the great commitment of leading personalities and great physicians, in particular: Joseph K. Perloff (USA), Gary Webb (Canada), Jane Somerville (UK), Carole Warnes (USA), Carlo Kallfelz, Peter Lange and John Hess (Germany).Just in time, all of them drew attention to this important and new area of cardiology and laid the foundation for optimized patient care.The medical care of ACHD has currently reached a high, unprecedented level.However, most CHD are repaired, but not fully corrected.Therefore, anatomical and functional residua and sequelae often exist.Patients are chronically ill and require lifelong care by specialists familiar with CHD in adulthood.Residua and sequelae, heart failure, cardiac arrhythmias, sudden cardiac death, or infective endocarditis, and, with increasing significance, acquired heart disease (e.g., coronary artery disease, valvular heart disease), pulmonary vascular disease, multi-organ complications or psychological and intellectual limitations adversely affect quality of life, performance, working ability and mental health of ACHD.Disease progression of these chronically ill patients is influenced by factors such as genetics, environment, diet, exercise, lifestyle, stress, occupation, socioeconomic status as well as education, culture and spirituality.In addition, non-cardiac comorbidities, inadequate or false health-related information on the clinical status, and adverse health and nutritional behavior and/or wrong physical activity are distressing factors.Therefore, despite major advances in the past, there remain still considerable challenges in the future.Still, too little attention is paid to the problems of chronic illness and there remain considerable supply deficits, especially in the areas of disease prevention, rehabilitation and holistic, innovative medical care.ACHD who are saved from premature death with a high medical, technical and financial burden and who are generally able to lead a nearly healthy live, often lose their ability to work too early and possibly many years of life because of insufficient education and care.To remedy these inadequately recognized deficits in ACHD care, congenital cardiologists should communicate and collaborate with specialists from other disciplines and other health professionals (such as physiotherapists, nutritionists, health economists, social workers, epidemiologists, psychologists).Prophylaxis and treatment programs should be developed for those affected to prevent, shorten or positively influence a chronic disease progression through preventive, accompanying and supportive measures.CDTs first of two focusses issues on ACHD gives a broad review and new data to illustrate what has been achieved, but also, and with major emphasize, discusses future options and direction in the diagnosis and therapy of ACHD.We provide appropriate, state-of-the-art knowledge, about diagnosis, treatment and disease prevention in order to improve medical care and salutogenesis of ACHD.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".