Abstract 19: Physical Activity After Chronic Total Occlusion PCI and Its Association With Health Status
Bibliographic record
Abstract
Introduction: Regular exercise provides multiple benefits to patients with coronary artery disease, but patients with chronic total occlusions (CTOs) may not participate in regular exercise due to refractory angina. There are few data to describe exercise participation after CTO PCI and the association of exercise patterns with health status after CTO PCI. Methods: We studied 1000 consecutive patients enrolled in OPEN CTO, a prospective 12 US center registry of CTO PCI. Participants were asked about participation in regular exercise (yes/no) at baseline and 12 months after CTO PCI, and the frequency of exercise (<1x/wk, 1-2x/wk, >=3x/wk) was collected among exercisers. Regular exercise included participation in any amount of exercise on a regular basis. Multivariable regression was used to compare 12-month health status change across 4 groups defined by exercise frequency at baseline and 12 months after CTO PCI [no regular exercise at baseline and 12 months, and reduced, increased, and consistent exercise at 12-months], adjusting for patient characteristics, technical success of the CTO PCI and completeness of revascularization. Health status was assessed using the Seattle Angina Questionnaire (SAQ) Angina Frequency (AF), Physical limitations (PL), Quality of life (QoL) and Summary Score (OS) domains. Results: A total of 869 patients with complete exercise data were included in the analysis. The proportion exercising regularly increased from 33.5% at baseline to 56.6% 12 months after CTO PCI (p < 0.01). Predictors of regular exercise at 12 months included baseline exercise, smoking, change in SAQ OS and baseline SAQ OS (Fig 1a). After multivariable adjustment, consistent or increased exercise frequency was associated with significantly greater improvement in SAQ PL, AF, Qol and OS scores ( p<0.01 for all, Fig 1b). Conclusion: Participation in regular exercise significantly increased 12 months after CTO PCI, and patients who had greater health status benefit after PCI were more likely to exercise regularly at 12 months. CTO PCI may enable CAD patients with limiting symptoms to engage in regular exercise. Further study of the association between health status improvement and exercise after CTO PCI is needed.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".