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Record W2905794790 · doi:10.1007/s13555-018-0279-5

Clinical Goals and Barriers to Effective Psoriasis Care

2018· article· en· W2905794790 on OpenAlex
Bruce Strober, Joelle M. van der Walt, April W. Armstrong, Marc Bourcier, André Vicente Esteves de Carvalho, Edgardo Chouela, Arnon D. Cohen, Charles N. Ellis, A.Y. Finlay, Alice B. Gottlieb, Jóhann E. Guðjónsson, Lars Iversen, C. Elise Kleyn, Craig L. Leonardi, Charles Lynde, Caitriona Ryan, Colin Theng, Fernando Valenzuela, Ronald Vender, Jashin J. Wu, Helen Young, Alexa B. Kimball

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueDermatology and Therapy · 2018
Typearticle
Languageen
FieldImmunology and Microbiology
TopicPsoriasis: Treatment and Pathogenesis
Canadian institutionsUniversity of TorontoUniversité de SherbrookeDermatrials ResearchProbity Medical Research
FundersCilagAllerganMedacAstellas PharmaGlenmark PharmaceuticalsNational Psoriasis FoundationPfizerIncyteDermiraSun PharmaRegeneron PharmaceuticalsUniversity of ConnecticutEli Lilly and CompanyCardiff UniversityCelgeneLEO PharmaOrtho DermatologicsGilead SciencesSanofiGlaxoSmithKlineGaldermaBristol-Myers SquibbMeiji Seika PharmaCoherus BiosciencesUCB PharmaValeant Pharmaceuticals InternationalAmgen
KeywordsPsoriasisPaceMedicineDiseaseIntensive care medicineAlternative medicineBusinessFamily medicineDermatologyPathology

Abstract

fetched live from OpenAlex

Engaging global key opinion leaders, the International Psoriasis Council (IPC) held a day-long roundtable discussion with the primary purpose to discuss the treatment goals of psoriasis patients and worldwide barriers to optimal care. Setting clear expectations might ultimately encourage undertreated psoriasis patients to seek care in an era in which great gains in therapeutic efficacy have been achieved. Here, we discuss the option for early treatment of all categories of psoriasis to alleviate disease impact while emphasizing the need for more focused attention for psoriasis patients with mild and moderate forms of this autoimmune disease. In addition, we encourage policy changes to keep pace with the innovative therapies and clinical science and highlight the demand for greater understanding of treatment barriers in resource-poor countries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.495
Threshold uncertainty score0.592

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.292
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it