Synthesis, Structures and DFT Computational Studies of [3.1.1]Metacyclophanes Containing Benzofuran Rings
Classification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Abstract [3.1.1]Metacyclophane ([3.1.1]MCP) 6 a containing two benzofuran rings was obtained by treatment of [3.3.3]MCP‐dione 5 with trimethylsilyl iodide. The precursor 5 was synthesized using ( p ‐tolylsulfonyl)methyl isocyanide (TosMIC) as the cyclization reagent. The 1 H‐NMR spectrum of 6 a at room temperature reveals that it undergoes very fast conformational changes relative to the NMR time scale and that the phenolic hydrogen forms weak intramolecular hydrogen bonding with the oxygen of one of the benzofurans. O ‐Methylation of 6 a afforded the calixarene analogue, macrocyclic [3.1.1]MCP 7 a whose 1 H‐NMR spectrum reveals that it adopts a cone‐likeconformation in solution at room temperature and the alkoxy group is pointing above and away from the macrocyclic cavity.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it