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Record W2908258859 · doi:10.1164/rccm.201812-2242ed

Smooth Muscle Cells: A Novel Site of P-Selectin Expression with Pathophysiological and Therapeutic Relevance in Pulmonary Hypertension

2018· letter· en· W2908258859 on OpenAlexafffund
Prithu Sundd, Wolfgang M. Kuebler

Bibliographic record

VenueAmerican Journal of Respiratory and Critical Care Medicine · 2018
Typeletter
Languageen
FieldMedicine
TopicPulmonary Hypertension Research and Treatments
Canadian institutionsMuscular Dystrophy CanadaUniversity of TorontoSt. Michael's Hospital
FundersUniversity of TorontoNational Heart, Lung, and Blood InstituteUniversity of Pittsburgh
KeywordsMedicinePathophysiologyPulmonary hypertensionCardiologyInternal medicine

Abstract

fetched live from OpenAlex

normal PAP is considered to be 14.0 6 3.3 mm Hg, at the 6th World Symposium on Pulmonary Hypertension held in Nice in 2018, a change in the definition of PAH was proposed that would decrease the lower limit of mPAP to 20 mm Hg and a pulmonary vascular resistance .3 WU; however, no conclusion was made regarding whether patients with an mPAP between 20 and 25 mm Hg should be treated (11).The ability to obtain an early diagnosis in PAH remains an important goal to be pursued.Sawada and colleagues have contributed to this quest by evaluating the performance of a large ECG-based screening program in healthy schoolchildren.Unfortunately, the studied screening program did not resolve this problem, and thus early diagnosis remains an important goal to pursue in children with PAH.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.010
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0100.008
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.297
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2018
Admission routes2
Has abstractyes

Explore more

Same venueAmerican Journal of Respiratory and Critical Care Medicine→Same topicPulmonary Hypertension Research and Treatments→French-language works237,207→