Relationship Between Respiratory Sensory Perception, Speech, and Swallow in Parkinson's Disease
Why this work is in the frame
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Bibliographic record
Abstract
ABSTRACT Background It has been suggested that sensory impairments contribute significantly to the motor deficits secondary to impaired sensorimotor integration in Parkinson's disease. Speech and swallowing are likely to become disordered in PD, and there is evidence that impaired upper airway sensation also contributes to these disorders. Objectives The goal of this study was to investigate the relationship between perception of general respiratory sensation, speech, and swallowing in PD. Methods Thirteen people with PD and 14 age‐equivalent controls volunteered to participate. Randomized blocks of inspiratory resistive loads were delivered, and participants gauged the magnitude of the loads using a modified Borg scale. The magnitude estimates were then compared to results of speech and swallowing evaluations using multivariate analysis of variance and a stepwise linear regression model. Results There was a significant overall interaction between the participant group (PD versus control) and respiratory load (F [10, 300] = 2.138; P = .022). A significant regression equation containing a predictor speech variable respiratory rating was found (F [1,22] = 6.946), P = .023), with a moderate effect size of R 2 = .387. Conclusions People with PD have blunted perception of respiratory resistive loads when compared with age‐equivalent healthy adults. Results also suggest that blunted ME of resistive loads could contribute to changes in respiratory drive for speech (i.e., loudness).
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it