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Record W2911593169 · doi:10.29252/jafm.75.253.28895

Study of Pulsatile Flow in Common Carotid Artery with Different Stenosis' Shapes within Various Wall Conditions

2019· article· en· W2911593169 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Applied Fluid Mechanics · 2019
Typearticle
Languageen
FieldMedicine
TopicCoronary Interventions and Diagnostics
Canadian institutionsYork University
Fundersnot available
KeywordsStenosisShear stressPulsatile flowMechanicsNewtonian fluidFlow (mathematics)MedicineMaterials scienceCardiologyPhysics

Abstract

fetched live from OpenAlex

Recently, due to the development of CFD techniques, many attempts have been made to simulate the initiation and progression of atherosclerosis. In recent works, various curves have been suggested to model the stenosis shape. However, little effort has been made to study the importance of the stenosis shape on the flow behavior. In this study, four types of stenosis with asteroid, Gaussian, semi-circle, and sinusoidal shapes were simulated in order to study the effect of the stenosis shape on flow behavior and diagnosis parameters. Shear stress and flow behavior were investigated in the common carotid artery with stenosis severities of 30%, 40%, and 50%. Flow was assumed to be unsteady and the inlet to be a pulsatile flow. Two cases of Newtonian and non-Newtonian fluids were simulated. The no-slip and permeable boundary conditions were imposed on the outer walls. To examine the effect of the location of stenosis, modeling was conducted at various locations. The results showed that the maximum shear stress occurs in the Gaussian stenosis at the opening of the stenosis. Semi-circle, sinus, and asteroid shapes had the next largest shear stress values. Additionally, the location of stenosis had a negligible effect on the maximum shear stress. However, flow resistance increased with increasing the stenosis’s distance from the beginning of the artery. This study indicates that stenosis shape highly affects the flow characteristics, and stenosis severity is not the only parameter that is important. Hence, the stenosis shape should be considered when simulating atherosclerosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.186
Threshold uncertainty score0.626

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.252
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it