Case Report: Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Sigmoiditis
Bibliographic record
Abstract
Purpose: Radiation colitis is not an uncommon consequence of pelvic radiation, such as in patients treated for gynecologic cancers. Some of these patients may suffer from anemia requiring transfusion due to chronic bleeding. Many of these patients are managed with rectal medications, which is often inadequate for control. Argon plasma coagulation (APC) has been well described for its efficacy in treating radiation proctitis. Here, we present two cases in which APC therapy was used to treat radiation sigmoiditis. Methods: We followed two cases originally seen at our regional cancer centre (Cross Cancer Institute) in Edmonton, Alberta, Canada. Both patients received pelvic radiation for endometrial cancers and were referred for active bleeding secondary to radiation colitis that had required numerous transfusions. Results: Radiation induced telangiectasias were found from 10–50 cm in the sigmoid colon. Both patients had significant improvement of symptoms after one session of APC treatment set at 40–60 W and gas flow of 2.0 L/min. To assess the efficacy of treatment, a second endoscopy with APC was performed. There were no complications from the procedures. Neither patient require blood transfusions after the initial treatment with improvement in their hemoglobin levels and were doing well at four and ten-month follow up. Conclusion: Argon plasma coagulation can be used effectively to provide immediate and sustained resolution of symptoms in patients with radiation sigmoiditis (colitis).
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".