Modeling Saccadic Action Selection: Cortical and Basal Ganglia Signals Coalesce in the Superior Colliculus
Bibliographic record
Abstract
The distributed nature of information processing in the brain creates a complex variety of decision making behavior. Likewise, computational models of saccadic decision making behavior are numerous and diverse. Here we present a generative model of saccadic action selection in the context of competitive decision making in the superior colliculus (SC) in order to investigate how independent neural signals may converge to interact and guide saccade selection, and to test if systematic variations can better replicate the variability in responses that are part of normal human behavior. The model was tasked with performing pro- and anti-saccades in order to replicate specific attributes of healthy human saccade behavior. Participants (ages 18-39) were instructed to either look toward (pro-saccade, well-practiced automated response) or away from (anti-saccade, combination of inhibitory and voluntary responses) a peripheral visual stimulus. They generated express and regular latency saccades in the pro-saccade task. In the anti-saccade task, correct reaction times were longer and participants occasionally looked at the stimulus (direction error) at either express or regular latencies. To gain a better understanding of the underlying neural processes that lead to saccadic action selection and response inhibition, we implemented 8 inputs inspired by systems neuroscience. These inputs reflected known sensory, automated, voluntary, and inhibitory components of cortical and basal ganglia activity that coalesces in the intermediate layers of the SC (SCi). The model produced bimodal reaction time distributions, where express and regular latency saccades had distinct modes, for both correct pro-saccades and direction errors in the anti-saccade task. Importantly, express and regular latency direction errors resulted from interactions of different inputs in the model. Express latency direction errors were due to a lack of pre-emptive fixation and inhibitory activity, which aloud sensory and automated inputs to initiate a stimulus-driven saccade. Regular latency errors occurred when the automated motor signals were stronger than the voluntary motor signals. While previous models have emulated fewer aspects of these behavioral findings, the focus of the simulations here is on the interaction of a wide variety of physiologically-based information integration producing a richer set of natural behavioral variability.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".