High‐flow nasal oxygen vs. standard flow‐rate facemask pre‐oxygenation in pregnant patients: a randomised physiological study
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Summary High‐flow nasal oxygen has been shown to provide effective pre‐oxygenation and prolong apnoeic time during intubation attempts in non‐pregnant patients. We aimed to compare pre‐oxygenation using high‐flow nasal oxygen (30–70 l.min −1 oxygen flow) via nasal prongs with standard 15 l.min −1 oxygen breathing via a tight‐fitting facemask. Forty healthy parturients were randomly allocated to these two groups, and furthermore each patient underwent the selected pre‐oxygenation method with both 3‐min tidal volume breathing and 30s tidal breathing followed by eight vital capacity breaths. With 3‐min tidal volume breathing, the respective estimated marginal means for high‐flow nasal oxygen and standard flow rate facemask pre‐oxygenation were 87.4% (95% CI 85.5–89.2%) and 91.0% (95% CI 89.3–92.7%), p = 0.02; with eight vital capacity breaths the estimated marginal means were 85.9% (95% CI 84.1–87.7%) and 91.8% (95% CI 90.1–93.4%, p < 0.0001). Furthermore, high‐flow nasal oxygen did not reliably achieve a mean end‐tidal oxygen concentration ≥ 90% compared with the standard flow rate facemask. In this physiological study, high‐flow nasal oxygen pre‐oxygenation performed worse than standard flow rate facemask pre‐oxygenation in healthy term parturients.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it