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Record W2917873343 · doi:10.1002/gepi.20274

Introduction to Genetic Analysis Workshop 15 summaries

2007· article· en· W2917873343 on OpenAlexfundno aff
John S. Witte, Audrey H. Schnell, Heather J. Cordell, Richard S. Spielman, Christopher I. Amos, Michael B. Miller, Laura Almasy, Jean W. MacCluer

Bibliographic record

VenueGenetic Epidemiology · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Mapping and Diversity in Plants and Animals
Canadian institutionsnot available
FundersNational Institute of General Medical SciencesNational Human Genome Research InstituteNational Institute on AgingNational Institutes of HealthNational Heart, Lung, and Blood InstituteGenome Canada
KeywordsComputational biologyGenetic analysisBiologyGeneticsComputer scienceGene

Abstract

fetched live from OpenAlex

The 15th biennial Genetic Analysis Workshop (GAW15) took place November 11-15, 2006 in St. Pete Beach, Florida. The workshop's primary focus was on the appropriate linkage, association, and other analyses of the increasingly large datasets generated by genetics research. A record number of participants (N=350) contributed 252 papers to GAW15. These contributions were organized into 17 presentation groups, with a range of 11 to 18 papers in each group (median of 15 papers per group). The data sets--or "problems"--for GAW15 included information from two real data sets and a simulated data set. The first problem utilizing real data included gene expression as the phenotype and genome-wide markers for linkage and association studies. The second problem allowed for detecting and characterizing genetic effects for rheumatoid arthritis. And the simulated problem was generated to reflect the data structure underlying the rheumatoid arthritis study. Further details on GAW15 are provided here, and the primary findings from the workshop are highlighted in the following group summary papers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.177
Threshold uncertainty score0.950

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.289
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2007
Admission routes1
Has abstractyes

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