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Record W2920368214 · doi:10.1002/9781119211419.ch5

Ulcer Disease and<i>Helicobacter Pylori</i>Infection: Current Treatment

2019· other· en· W2920368214 on OpenAlexaff
Naoki Chiba

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicHelicobacter pylori-related gastroenterology studies
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicineHelicobacter pyloriGastroenterologyInternal medicineEtiologyDiseaseAspirinPeptic ulcerPerforationOmeprazolePeptic

Abstract

fetched live from OpenAlex

Peptic ulcers diseases (PUD) were thought to be caused by a variety of cofactors such as smoking, stress, and nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin. This chapter presents the evidence for the etiological role of Helicobacter pylori in PUD. It considers the prevalence of H. pylori in both duodenal and gastric ulcer patients. The chapter demonstrates the temporal relationship between infection with H. pylori and the development of duodenal ulcer. The clinically relevant evidence for the role of H. pylori comes from intervention trials in which H. pylori was eradicated and recurrence of ulcer disease markedly reduced. The highest risk for ulcer perforation was identified in a cohort of men born between 1900 and 1920. There are only two recommended first-line empiric therapies: non-bismuth quadruple therapy, bismuth quadruple therapy for H. pylori eradication. The potent acid suppressive drugs are potent acid suppressing agents that effectively heal duodenal and gastric ulcers and provide prompt symptom relief.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.015
Threshold uncertainty score0.049

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0150.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.282
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2019
Admission routes1
Has abstractyes

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