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Record W2921259698 · doi:10.1016/s1474-4422(19)30069-9

Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial

2019· article· en· W2921259698 on OpenAlexafffund
Magdy Selim, Lydia D. Foster, Claudia S. Moy, Guohua Xi, Michael D. Hill, Lewis B. Morgenstern, Steven M. Greenberg, Michael L. James, Vineeta Singh, Wayne M. Clark, Casey Norton, Yuko Y. Palesch, Sharon D. Yeatts, Monica Dolan, Erlinda Yeh, Kevin N. Sheth, Kimberly Kunze, Susanne Muehlschlegel, Iryna Nieto, Jan Claassen, Cristina Falo, David Huang, Anne Beckwith, Steven R. Messé, Melissa A. Yates, Kristine O’Phelan, Andrea Escobar, Kyra J. Becker, Patricia Tanzi, Nicole R. Gonzales, Chad Tremont, Chitra Venkatasubramanian, Rosita Thiessen, Supriya Save, Steven Verrault, Karin Collard, Michael DeGeorgia, Valerie Cwiklinski, Bradford Thompson, Lesley Wasilewski, Charles Andrews, Robert Burfeind, Michel Torbey, Mohammad Hamed, Kenneth Butcher, Leka Sivakumar, Nicolaou Varelas, Kathleen Mays-Wilson, Enrique C. Leira, Heena Olalde, Scott Silliman, Rhonda Calhoun, Neha Dangayach, Ricardo Renvill, Rishi Malhotra, Kristina Kordesch, Aaron Lord, Thomas Calahan, Romergryko G. Geocadin, Michelle Burke Parish, James L. Frey, Mary Harrigan, Dana Leifer, Ryna Mathias, Michael Schneck, Tara Bernier, Sergio Gonzales-Arias, Josette Elysée, George Α. Lopez, Josephine Volgi, Robert H. Brown, Sara Jasak, Stephen Phillips, J Jarrett, João Gomes, Moneen McBride, François Aldrich, Charlene Aldrich, Joshua Kornbluth, Michelle Bettle, Joshua N. Goldstein, Gregory Philip Tirrell, Qaisar Shaw, Karin Jonczak

Bibliographic record

VenueThe Lancet Neurology · 2019
Typearticle
Languageen
FieldMedicine
TopicIntracerebral and Subarachnoid Hemorrhage Research
Canadian institutionsUniversity of Calgary
FundersNational Institutes of HealthCanadian Institutes of Health ResearchHealth CanadaMedical University of South CarolinaNational Institute of Neurological Disorders and StrokeAmerican Heart Association
KeywordsMedicinePlaceboPopulationModified Rankin ScaleDeferoxamineIntention-to-treat analysisClinical trialRandomized controlled trialIntracerebral hemorrhageInternal medicineSurgeryGlasgow Coma ScalePathology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.305
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations249
Published2019
Admission routes2
Has abstractno

Explore more

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