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Record W2921426987 · doi:10.1289/isee.2014.s-019

The Science of Low-Level Lead Toxicity

2014· article· en· W2921426987 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueISEE Conference Abstracts · 2014
Typearticle
Languageen
FieldEnvironmental Science
TopicHeavy Metal Exposure and Toxicity
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsBlood lead levelLead poisoningEnvironmental healthLead exposureToxicantLead (geology)MedicineDiseasePublic healthRisk factorPsychopathologyGerontologyToxicityPsychiatryPathologyBiology

Abstract

fetched live from OpenAlex

The Science of Low-Level Lead ToxicityAbstract Number:2909 Bruce Lanphear* Bruce Lanphear* Simon Fraser University, Canada, E-mail Address: [email protected] AbstractLow levels of exposure to lead, the prototypical toxicant, are associated with an increased risk of disability and disease. In children, low-level lead exposure impacts the developing brain and is linked with diminished intelligence, ADHD, and antisocial behaviors. There is no apparent threshold for lead toxicity; indeed, for a given exposure, the decrements in intellectual function are greater at blood lead levels < 100 µg/L (i.e., <10 µg/dL), the level still considered 'acceptable' in many countries. Lead exposure is also a major risk factor for psychopathology, including ADHD and criminal behaviors. In the United States, 1 in 5 cases of ADHD have been attributed to lead exposure and the decline in blood lead levels was cited as the major reason for the dramatic decline in violent crimes over the past 5 decades. In adults, lead exposure is an established risk factor for hypertension and chronic renal failure. Lead is also a potential risk factor for some of the most prevalent causes of deaths and disabilities in industrialized societies, such as cardiovascular disease mortality and accelerated cognitive decline. Evidence is emerging that these health impacts occur at blood lead levels well below current health standards and guidelines. Despite the dramatic declines in blood lead concentrations that have been achieved in many countries, low-level lead toxicity remains a major public health problem worldwide; a large fraction of children in many industrializing countries have blood lead levels in excess of 100 µg/L and the cost of lead toxicity exceeds $1 trillion annually.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.511
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.256
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it