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Record W2921479503 · doi:10.1117/12.2503907

Hyperspectral imaging for intraoperative diagnosis of colon cancer metastasis in a liver

2019· article· en· W2921479503 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldEngineering
TopicRemote-Sensing Image Classification
Canadian institutionsPhoton Etc (Canada)
Fundersnot available
KeywordsHyperspectral imagingH&E stainCancerMetastasisMedicineColorectal cancerLiver cancerRadiologyColonic cancerPathologyInternal medicineArtificial intelligenceImmunohistochemistryComputer science

Abstract

fetched live from OpenAlex

Hyperspectral imaging (HSI) is being shown as an emerging modality with a great potential in disease diagnosis and surgical cancer resection. Herein, we evaluate feasibility of the HSI to discriminate and diagnose colon cancer metastasis in a liver from five hematoxylin and eosin stained histopathological specimens. They were collected from the same patient during intraoperative frozen section analysis. Cancer and non-cancer spectra along with corresponding spatial maps were estimated from hyperspectral images by means of spectral unmixing. It was found that maximal angle between cancer spectra is 1.02 degrees less than minimal angle between cancer vs. non-cancer spectra. Thus, spectrum angle mapper was used for pixel-based diagnosis of cancer yielding sensitivity between 81.23% and 97.12%, specificity between 85.85% and 97.3%, and accuracy between 86.85% and 96.92%.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.475
Threshold uncertainty score0.318

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.252
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations10
Published2019
Admission routes1
Has abstractyes

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