Presenilin Function: Connections to Alzheimer's Disease and Signal Transduction
Bibliographic record
Abstract
Conference Abstract| February 01 2000 Presenilin Function: Connections to Alzheimer's Disease and Signal Transduction P.E. Fraser; P.E. Fraser 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar G. Yu; G. Yu 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar M. Nishimura; M. Nishimura 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar L. Lévesque; L. Lévesque 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar H.T.J. Mount; H.T.J. Mount 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar D. Westaway; D. Westaway 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar P. St George-Hyslop P. St George-Hyslop 1Centre for Research in Neurodegenerative Diseases, Depts. of Medical Biophysics, Medicine (Neurology), Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada MSS 3H2 Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (2000) 28 (1): A16. https://doi.org/10.1042/bst028a016 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share MailTo Twitter LinkedIn Cite Icon Cite Get Permissions Citation P.E. Fraser, G. Yu, M. Nishimura, L. Lévesque, H.T.J. Mount, D. Westaway, P. St George-Hyslop; Presenilin Function: Connections to Alzheimer's Disease and Signal Transduction. Biochem Soc Trans 1 February 2000; 28 (1): A16. doi: https://doi.org/10.1042/bst028a016 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 2000 Biochemical Society2000 Article PDF first page preview Close Modal You do not currently have access to this content.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.007 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".