Primary Neurolymphomatosis in the Cavernous Sinus and the Brainstem
Bibliographic record
Abstract
Primary neurolymphomatosis is a rare condition that refers to lymphomas primarily presenting in cranial or peripheral nerves. Similar to primary central nervous system lymphoma (PCNSL), almost all cases of neurolymphomatosis are histologically classified as high-grade diffuse B cell lymphoma. Primary involvement of cranial nerves is extremely rare and manifests with signs and symptoms of mass effect. We present the case of a 67-year-old right-handed male who presented to hospital with progressive horizontal diplopia and left facial numbness in the V1 and V2 distributions. The patient subsequently developed ataxia, dizziness and nausea. An open biopsy was performed which confirmed the diagnosis of diffuse B cell lymphoma. The patient experienced rapid clinical improvement after the administration of chemotherapy and radiotherapy. We also review previous reports of primary neurolymphomatosis in the cavernous sinus. However, to our knowledge, this is the first case with concurrent involvement of the cerebellopontine angle.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".