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Record W2922564321 · doi:10.1002/cnm.3200

A finite difference method with subsampling for immersed boundary simulations of the capsule dynamics with viscoelastic membranes

2019· article· en· W2922564321 on OpenAlexafffund
Ping Li, Junfeng Zhang

Bibliographic record

VenueInternational Journal for Numerical Methods in Biomedical Engineering · 2019
Typearticle
Languageen
FieldMedicine
TopicBlood properties and coagulation
Canadian institutionsLaurentian University
FundersNatural Sciences and Engineering Research Council of CanadaOntario Trillium Foundation
KeywordsViscoelasticityImmersed boundary methodCapsuleMembraneFinite difference methodDynamics (music)MechanicsFinite differenceMaterials scienceBoundary value problemBoundary (topology)Classical mechanicsMathematicsMathematical analysisPhysicsComposite materialAcousticsChemistryGeology

Abstract

fetched live from OpenAlex

The membrane or interfacial viscosity is an important property in many multiphase and biofluidic situations, such as the red blood cell dynamics and emulsion stability. The immersed boundary method (IBM), which incorporates the dynamic flow-membrane interaction via force distribution and velocity interpolation, has been extensively employed in simulations of such systems. Unfortunately, direct implementation of membrane viscosity in IBM suffers severe numerical instability, which causes an IBM calculation to break down before generating any useful results. Few attempts have been recently reported; however, several concerns exist in these attempts, such as the inconsistency to the classical definition of membrane viscosity, the inability to model the shear and dilatational viscosities separately, the unjustified mathematical formulations, and the complicated algorithms and computation. To overcome these concerns, in this paper, we propose a finite difference approach for implementing membrane viscosity in immersed boundary simulations. The viscous stress is obtained via finite difference approximations to the differential strain-stress relationship, with the help of a subsampling scheme to reduce the numerical noise in the calculated strain rates. This simple method has also avoided the complicated matrix calculations in previous attempts, and hence, a better computational efficiency is expected. Detailed mathematical description of the method and key steps for its implementation in immersed boundary programs are provided. Validation and illustration calculations are performed, and our results are compared with analytical solutions and previous publications with satisfactory agreement. The influences of membrane mesh resolution and simulation time step are also examined; and the results show no indication that our finite difference method has downgraded the general IBM accuracy. Based on these simulations and analysis, we believe that our method would be a better choice for future IBM simulations of capsule dynamics with viscoelastic membranes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.005
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.353
Teacher spread0.333 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations29
Published2019
Admission routes2
Has abstractyes

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