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Record W2927267696 · doi:10.1101/598888

A generalization of partial least squares regression and correspondence analysis for categorical and mixed data: An application with the ADNI data

2019· preprint· en· W2927267696 on OpenAlexafffund
Derek Beaton, Gilbert Saporta, Hervé Abdi

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2019
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicSensory Analysis and Statistical Methods
Canadian institutionsBaycrest Hospital
FundersNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchNational Institutes of HealthGenentechIXICOH. Lundbeck A/SServierEisaiNorthern California Institute for Research and EducationNovartis Pharmaceuticals CorporationBioClinicaU.S. Department of DefenseMeso Scale DiagnosticsAlzheimer's Disease Neuroimaging InitiativeBiogenEli Lilly and CompanyBristol-Myers SquibbNational Institute on AgingAlzheimer's AssociationFoundation for the National Institutes of Health
KeywordsPartial least squares regressionCategorical variableMultivariate statisticsOrdinal dataPartial correlationRegressionGeneralizationRegression analysisCanonical correlationData miningComputer scienceStatisticsMathematicsArtificial intelligenceCorrelation

Abstract

fetched live from OpenAlex

Abstract Current large scale studies of brain and behavior typically involve multiple populations, diverse types of data (e.g., genetics, brain structure, behavior, demographics, or “mutli-omics,” and “deep-phenotyping”) measured on various scales of measurement. To analyze these heterogeneous data sets we need simple but flexible methods able to integrate the inherent properties of these complex data sets. Here we introduce partial least squares-correspondence analysis-regression (PLS-CA-R) a method designed to address these constraints. PLS-CA-R generalizes PLS regression to most data types (e.g., continuous, ordinal, categorical, non-negative values). We also show that PLS-CA-R generalizes many “two-table” multivariate techniques and their respective algorithms, such as various PLS approaches, canonical correlation analysis, and redundancy analysis (a.k.a. reduced rank regression).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.041
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.020
Threshold uncertainty score0.104

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.041
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.005
Bibliometrics0.0030.005
Science and technology studies0.0010.002
Scholarly communication0.0020.002
Open science0.0030.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.296
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2019
Admission routes2
Has abstractyes

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