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Record W2930129875

Is Axial Psoriatic Arthritis distinct from Ankylosing Spondylitis with and without Psoriasis

2018· dissertation· en· W2930129875 on OpenAlexfundno aff
Joy Feld

Bibliographic record

VenueTSpace (University of Toronto) · 2018
Typedissertation
Languageen
FieldMedicine
TopicSpondyloarthritis Studies and Treatments
Canadian institutionsnot available
FundersKrembil Foundation
KeywordsPsoriatic arthritisAnkylosing spondylitisPsoriasisDermatologyMedicineSpondylitisSurgery
DOInot available

Abstract

fetched live from OpenAlex

Hypotheses: 1. Unilateral grade 2 sacroiliitis does not necessarily progress in psoriatic arthritis (PsA) 2. Ankylosing spondylitis (AS) with psoriasis and axial PsA are different phenotypes of the same disease Methods: Retrospective observational cohort study. Results: Progression of unilateral grade 2 sacroiliitis was seen in 52% of the PsA cohort, it was associated with: elevated ESR, short disease duration, young age and less degenerative disc disease. AS patients compared to axial PsA were more men, more likely to have HLA-B*27, had worse axial disease and milder peripheral arthritis. Concomitant psoriasis in AS did not influence the course of the disease. Discussion: Unilateral grade 2 sacroiliitis does not necessarily progress in PsA. The differences between axial PsA and AS, with and without psoriasis, were substantial, suggesting these are separate diseases with overlapping features. The presence of psoriasis in AS patients does not seem to affect the disease course.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.251
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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