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Record W2932024076 · doi:10.11575/prism/36155

Accelerating Sequence Calculations on Parallel GPU Architecture

2019· dissertation· en· W2932024076 on OpenAlexfundno aff
Roksana Hossain

Bibliographic record

VenuePRISM (University of Calgary) · 2019
Typedissertation
Languageen
FieldComputer Science
TopicParallel Computing and Optimization Techniques
Canadian institutionsnot available
FundersAlberta Innovates
KeywordsParallel computingArchitectureComputer scienceSequence (biology)CUDAComputational scienceComputer architectureChemistryGeography

Abstract

fetched live from OpenAlex

In this thesis, I have implemented a GPU (graphics processor unit) based sequencing algorithm that finds a sequence or order among data points to optimize a given objective. I have studied the sequencing algorithm as a path planner for an unmanned aerial vehicle (UAV) and also, a basecaller for a miniature DNA sequencer. Parallel implementation utilizing GPU enables faster processing and decision making that are important when data is quite large and a real-time response is critical e.g., in UAV based transportation. The goal of using UAV in my thesis is to construct a wireless sensor network in a remote location by deploying wireless sensor nodes. The proposed path planner, also known as a sequencer, is designed to find the shortest path that is also a safe path using travelling salesman problem. A path is considered safe when the vehicle would not collide with any obstacle. Two sets of heuristic algorithms, one for generating a sequence of waypoints (sequence generator) and another one for constructing a path between two waypoints (path explorer), are used to find the near optimal solution. The highly-parallel multicore GPU is used for the real-time implementation that offloads compute-intensive portions from the traditional CPU to the GPU to make the decision-making process faster. In this thesis, the parallel execution of the sequence generator and the path explorer achieved a 4.82x and 164x speed-up compared to the CPU-only approach respectively. The second sequencer is a palm-sized miniature DNA sequencer, the so-called MinION device. In the case of the MinION, a vast multitude of DNA strands are introduced into the device and converted into noisy electronic time-series signals; these measurements are essentially physical signatures related to the molecular make-up of the sensed DNA. Among a long "pipeline" of analysis steps to be performed on such measurement sequences, the first, and arguably most intensive, is the so-called basecalling step which analyzes the time-series and converts it into the equivalent monomeric base of the DNA under test using the Viterbi algorithm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.012
Threshold uncertainty score0.041

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0120.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.244
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2019
Admission routes1
Has abstractyes

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