MétaCan
Menu
Back to cohort
Record W2937275214 · doi:10.1093/sleep/zsz067.745

0747 Medications Prescribed For Sleep Problems In Children And Adolescents With Psychiatric Disorders.

2019· article· en· W2937275214 on OpenAlexaffabout
Nadia Khebchi, Marjolaine Chicoine, Roger Godbout

Bibliographic record

VenueSLEEP · 2019
Typearticle
Languageen
FieldMedicine
TopicAttention Deficit Hyperactivity Disorder
Canadian institutionsUniversité de MontréalHôpital Rivière-des-Prairies
Fundersnot available
KeywordsBedtimeMedicinePsychiatryAttention deficit hyperactivity disorderPediatricsAutismAutism spectrum disorderPervasive developmental disorder

Abstract

fetched live from OpenAlex

Up to 90% of children and adolescents with a psychiatric diagnosis also suffer from sleep disorders, thus worsening their diurnal symptoms. Most of these children are prescribed medications to help them cope with their sleep difficulties. We analyzed the medical files of patients referred to the sleep clinic of a pediatric mental health hospital. The medical charts of 401 patients diagnosed with or being evaluated for a psychiatric disorder and referred to the sleep clinic of a pediatric mental health hospital were reviewed by two judges with full access to the complete hospital file of each patient. The mean age of patients was 8.4 ± 4.7 years and 67% were boys. The most frequent primary diagnoses were Autism Spectrum Disorder (ASD, 39.4%) and Attention Deficit Hyperactivity Disorder (ADHD, 28.7%). A majority of patients (81.2%) was either referred by a pediatrician (42.8%) or a psychiatrist (38.4%). At intake, all diagnoses being combined, 78.5% of patients were taking melatonin, a product available over-the-counter in Canada. Antipsychotics (18.9%), antidepressants (10.7%) and clonidine (also 10.7%) were the most prescribed medications at bedtime. In ASD and ADHD more specifically, antipsychotics were the most prescribed medication at bedtime, with 23.4% and 29.6% of patients, respectively. Melatonin was reported as the most frequent sleep aid taken by patients upon their arrival at the sleep clinic but dosage and timing varied greatly, pointing toward a knowledge gap in parents, prescribers, providers and/or advisors. The use of antipsychotics at bedtime in children and adolescents is alarming, given the fact that there is no published scientific evidence to support their use. Support (If Any)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.504

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.255
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes2
Has abstractyes

Explore more

Same venueSLEEPSame topicAttention Deficit Hyperactivity DisorderFrench-language works237,207