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Determination of antiemetic, antimicrobial and anti-radical properties of two plants of Apiaceae family growing in Bangladesh

2019· article· en· W2944520315 on OpenAlexvenueno aff
Nor Mohammad

Bibliographic record

VenueDiscovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology · 2019
Typearticle
Languageen
FieldMedicine
TopicMedicinal Plants and Neuroprotection
Canadian institutionsnot available
Fundersnot available
KeywordsFoeniculumApiaceaeAntimicrobialCentellaDPPHTraditional medicineChemistryAntiemeticAscorbic acidPharmacologyBiologyFood scienceBotanyAntioxidantMedicineBiochemistryVomitingSurgeryOrganic chemistry

Abstract

fetched live from OpenAlex

Objectives: This study was conducted to investigate the antiemetic, antimicrobial and anti-radical properties of two plants of Apiaceae family named Foeniculum vulgare and Centella asiatica. Materials and Methods: The antiemetic assay was carried out by using chick emetic model with minor modifications by calculating the mean decrease in the number of retching. The antimicrobial activity of the crude extract was performed by Disc Diffusion method. The anti-radical activity was determined by the 2, 2-diphenyl-2-picrylhydrazyl hydrate (DPPH) method.Results: The anti-emetic activity of the selected two plants on young chicks revealed that these extracts have a less anti-emetic effect. The group of chicks treated with Chlorpromazine was found to have 38.4 retches as compared to the 60.4 retches of the control group, thus Chlorpromazine reduced the retches by 36.96%. The chickens treated with Foeniculum vulgare and Centella asiatica extracts inhibited the retches up to 7.01% and 15.67% accordingly. The minimum antimicrobial effect was found in these two crude extracts. Both of these extracts did not appear potent in terms of both zones of inhibition and spectrum of activity. In anti-radical activity test, the Foeniculum vulgare and Centella asiatica showed moderate free radical scavenging activity with IC50 value 240.39 μg/ml and 241.71% respectively while compared to that of the reference standard ascorbic acid. Conclusion: The selected two plants of Apiaceae family possess less anti-emetic, minimum anti-microbial and moderate anti-radical activities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.356
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2019
Admission routes1
Has abstractyes

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