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Record W2945543852 · doi:10.20529/ijme.2019.016

Starting the conversation: CRISPR’s role in India

2019· article· en· W2945543852 on OpenAlexaff
Farhad R. Udwadia, Shivam Singh

Bibliographic record

VenueIndian Journal of Medical Ethics · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsNeuroDevNetUniversity Health NetworkUniversity of British Columbia
Fundersnot available
KeywordsCRISPRSociocultural evolutionConversationContext (archaeology)BusinessInternet privacyPolitical sciencePublic relationsSociologyBiologyComputer scienceLawGeneGeneticsCommunication

Abstract

fetched live from OpenAlex

The applications of gene editing technologies such as CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) have grown significantly in recent years. Several countries have adopted different stances on the regulation of such technology; however, India does not have any legally enforceable regulations in place. There is a need for such a development as India's regulatory, sociocultural, and economic landscape is unique. First, we discuss the uncertainty regarding India's regulatory capacity to enforce ethical standards for CRISPR use. Then, we discuss unique driving forces that could lead to the misuse of CRISPR in India, such as certain sociocultural norms like preferences for fair skin and public demand for sex determination. Given these previous concerns, we posit the question; where on the priority list does CRISPR stand in the context of public health in India?

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.246
Threshold uncertainty score0.476

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.329
Teacher spread0.319 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2019
Admission routes1
Has abstractyes

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