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Record W2948459395 · doi:10.33265/polar.v38.3366

Dynamics and persistence of rabies in the Arctic

2019· article· en· W2948459395 on OpenAlex
Audrey Simon, Olivia Tardy, Amy Hurford, Nicolas Lecomte, Denise Bélanger, Patrick A. Leighton

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenuePolar Research · 2019
Typearticle
Languageen
FieldImmunology and Microbiology
TopicRabies epidemiology and control
Canadian institutionsUniversité de MonctonMemorial University of NewfoundlandUniversité de Montréal
FundersNatural Sciences and Engineering Research Council of CanadaMinistère de la SantéCanada Research ChairsArcticNetMinistère de la Santé et des Services sociaux
KeywordsRabiesVulpesArctic foxArcticLagopusPopulationEcologyGeographyBiologyPredationDemographyVirology

Abstract

fetched live from OpenAlex

Rabies is a major issue for human and animal health in the Arctic, yet little is known about its epidemiology. In particular, there is an ongoing debate regarding how Arctic rabies persists in its primary reservoir host, the Arctic fox (Vulpes lagopus), which exists in the ecosystem at very low population densities. To shed light on the mechanisms of rabies persistence in the Arctic, we built a susceptible–exposed–infectious–recovered (SEIR) epidemiological model of rabies virus transmission in an Arctic fox population interacting with red foxes (Vulpes vulpes), a rabies host that is increasingly present in the Arctic. The model suggests that rabies cannot be maintained in resource-poor areas of the Arctic, characterized by low Arctic fox density, even in the presence of continuous reintroduction of the virus by infected Arctic foxes from neighbouring regions. However, in populations of relatively high Arctic fox density, rabies persists under conditions of higher transmission rate, prolonged infectious period and for a broad range of incubation periods. Introducing the strong cyclical dynamics of Arctic prey availability makes simulated rabies outbreaks less regular but more intense, with an onset that does not neatly track peaks in Arctic fox density. Finally, interaction between Arctic and red foxes increases the frequency and/or the intensity of rabies outbreaks in the Arctic fox population. Our work suggests that disruption of prey cycles and increasing interactions between Arctic and red foxes due to climate change and northern development may significantly change the epidemiology of rabies across the Arctic.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score0.244

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.332
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it