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Record W2949530306 · doi:10.1186/s12917-019-1943-4

Control of paratuberculosis: who, why and how. A review of 48 countries

2019· review· en· W2949530306 on OpenAlexaff
Richard J. Whittington, Karsten Donat, M.F. Weber, D.F. Kelton, Søren Saxmose Nielsen, Suzanne Eisenberg, N. Arrigoni, Ramón A. Juste, José Luis Sáez, Navneet K. Dhand, Annalisa Santi, Anita L. Michel, Herman W. Barkema, Petr Králík, Polychronis Kostoulas, Lorna Citer, Frank Griffin, Rob Barwell, Maria Aparecida Scatamburlo Moreira, Iva Slaná, Heike Koehler, Shoor Vir Singh, Han Sang Yoo, Gilberto Chávez-Gris, Amador Goodridge, M. Ocepek, Joseba M. Garrido, Karen Stevenson, Mike Collins, Bernardo Alonso, Karina Mariela Cirone, Fernando Paolicchi, Lawrence Gavey, Md. Tanvir Rahman, Emmanuelle De Marchin, Willem Van Praet, C.A. Bauman, Gilles Fecteau, Shawn McKenna, Miguel Salgado, Jorge A. Fernández-Silva, Radka Dziedzinská, Gustavo A. Echeverría, Jaana Seppänen, Virginie Thibault, Vala Friðriksdóttir, Abdolah Derakhshandeh, Masoud Haghkhah, Luigi Ruocco, Satoko Kawaji, Eiichi Momotani, C. Heuer, Solis Norton, Simeon Cadmus, Angelika Agdestein, Annette H. Kampen, J. Szteyn, Jenny Frössling, Ebba Schwan, George Caldow, Sam Strain, Mike Carter, Scott J. Wells, Musso Munyeme, Robert Wolf, Ratna B. Gurung, Cristóbal Verdugo, Christine Fourichon, Takehisa Yamamoto, Sharada Thapaliya, E. Di Labio, Monaya Ekgatat, Andrés Delgado Gil, Alvaro Nuñez Alesandre, José Piaggio, Alejandra Suanes, Jacobus H. de Waard

Bibliographic record

VenueBMC Veterinary Research · 2019
Typereview
Languageen
FieldMedicine
TopicMycobacterium research and diagnosis
Canadian institutionsUniversity of Prince Edward IslandUniversité de MontréalUniversity of CalgaryUniversity of Guelph
Fundersnot available
KeywordsParatuberculosisLivestockPublic healthGovernment (linguistics)Animal husbandryAnimal welfareBusinessBiosecurityFlockWildlifeWelfareVeterinary medicineEnvironmental healthGeographyAgricultureMedicinePolitical scienceTuberculosisBiologyMycobacterium

Abstract

fetched live from OpenAlex

Paratuberculosis, a chronic disease affecting ruminant livestock, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). It has direct and indirect economic costs, impacts animal welfare and arouses public health concerns. In a survey of 48 countries we found paratuberculosis to be very common in livestock. In about half the countries more than 20% of herds and flocks were infected with MAP. Most countries had large ruminant populations (millions), several types of farmed ruminants, multiple husbandry systems and tens of thousands of individual farms, creating challenges for disease control. In addition, numerous species of free-living wildlife were infected. Paratuberculosis was notifiable in most countries, but formal control programs were present in only 22 countries. Generally, these were the more highly developed countries with advanced veterinary services. Of the countries without a formal control program for paratuberculosis, 76% were in South and Central America, Asia and Africa while 20% were in Europe. Control programs were justified most commonly on animal health grounds, but protecting market access and public health were other factors. Prevalence reduction was the major objective in most countries, but Norway and Sweden aimed to eradicate the disease, so surveillance and response were their major objectives. Government funding was involved in about two thirds of countries, but operations tended to be funded by farmers and their organizations and not by government alone. The majority of countries (60%) had voluntary control programs. Generally, programs were supported by incentives for joining, financial compensation and/or penalties for non-participation. Performance indicators, structure, leadership, practices and tools used in control programs are also presented. Securing funding for long-term control activities was a widespread problem. Control programs were reported to be successful in 16 (73%) of the 22 countries. Recommendations are made for future control programs, including a primary goal of establishing an international code for paratuberculosis, leading to universal acknowledgment of the principles and methods of control in relation to endemic and transboundary disease. An holistic approach across all ruminant livestock industries and long-term commitment is required for control of paratuberculosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.011
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.005
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0060.010
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.290
GPT teacher head0.484
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations324
Published2019
Admission routes1
Has abstractyes

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