Results of application of chemical destruction in complex treatment of focal hepatic pathology
Bibliographic record
Abstract
Objective. To estimate the immediate results of application of chemical destruction with 10% solution of calcium chloride in complex of treatment in the patients, suffering focal hepatic pathology. Маterials and methods. In 2012 - 2019 yrs, using chemical destruction, the impact was delivered towards 104 tumoral foci (range from 1 tо 4) in the patients, suffering hepatocellular carcinoma (23.7%), colorectal cancer metastases (55.3%) and in noncolorectal cancer (21.1%). The foci diameter have constituted at average (2.60 ± 1.24) сm (in 1.0 - 4.0 сm range). Chemical ablation was performed, using injections of 10% solution of calcium chloride. Side-effects and answer of tumoral foci were estimated. Results. The specific postoperative complications rate (formation of abscesses in zone of destruction, development of hematomas and biliomas) have constituted 10.5%. There were observed a complete answer in the foci 1.0 - 1.5 сm in diameter, while the disease progress - concerning the foci 3,8 - 4,2 сm in diameter. Local recurrence have occurred in 15.8% patients. The answer degree trustworthily depended upon the tumoral foci density (r=0.529, р < 0.001). Including, complete answering was observed in 76.9% hypodense, 23.1% іsodense foci, and partial - concerning 37.8% hypodense, 29.7% іsodense and 32.4% of the foci of mixed structure. Stabilization of the disease was diagnosed, concerning 15.0% іso- and hypodense, 40.0% hyperdense and 45.0% with the foci of mixed structure, while a progress - concerning 85.7% hyperdense and 14.3%of the foci of mixed density. Conclusion. Іntratumoral injection of 10% solution of calcium chloride in the treatment of focal hepatic pathology is not accompanied by severe specific complications and mortality, the patients are survive the procedure satisfactory, which may be applied as a local tumoral control of tumoral foci up to 3.0 сm in diameter.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".